Pepperoni Pizza Grilled Cheese

Featured in Delicious Main Course Recipes for Every Occasion.

Layer bread with mozzarella and pepperoni, grill until melty, brush with seasoned garlic butter and finish grilling. Ready in 10 minutes.
Mena
Updated on Mon, 24 Feb 2025 10:17:34 GMT
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Let me tell you about the sandwich that changed my late-night snack game forever. During one of those can't-sleep moments when both pizza and grilled cheese sound perfect, I started playing around in the kitchen and stumbled onto this beautiful mash-up. It's like if a grilled cheese and a pizza had a really delicious baby.

Found myself making this at 2 AM last week and my roommate actually hugged me after trying it. Now it's our official movie night food.

Essential Ingredients:

  • Good bread is crucial - the thicker and sturdier, the better
  • Real mozzarella cheese - none of that pre-shredded business
  • Pepperoni needs to be the good stuff - those little cups of grease are gold
  • Fresh garlic butter makes everything better
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Detailed Instructions:

Butter Base
Get your pan nice and warm - not too hot or you'll burn the bread before the cheese melts.
Layering Love
Stack those ingredients like you're building the world's best sandwich tower.
Flip Skills
Use your biggest spatula and say a little prayer - confidence is key here.
Garlic Glory
Brush that garlic butter on like you're painting a masterpiece.
Final Touch
Give it a last crisp in the pan until it's golden perfection.

Last time I made these, my brother actually took pictures before eating. That's when you know you've created something special.

Sandwich Secrets

Listen, I've made this sandwich so many times now I could probably do it blindfolded. The trick I discovered after about my hundredth try? Adding that second layer of cheese on both sides traps the pepperoni in a gooey nest of melty goodness. And microwaving the pepperoni first? Total game-changer. No more soggy bread from pepperoni grease!

Perfect Partners

Dunk this bad boy in warm marinara sauce and you'll think you've died and gone to Italian heaven. Sometimes I'll whip up a quick garlic aioli for dipping too. Want to get fancy? Throw together a simple Caesar salad on the side - makes it feel like a proper meal instead of just amazing midnight munchies.

Switch It Up

Make this sandwich your own by playing around with the fillings. Sometimes I'll add fresh basil when I'm feeling fancy, or throw in some hot honey for a sweet-spicy kick. My friend Mark adds banana peppers to his, and honestly? Not mad about it. During summer, I'll sneak in a slice of fresh tomato - it's like a caprese met a pizza and they fell in love.

Keep It Crispy

These are best eaten straight off the pan when the cheese is all stretchy and the bread is still super crispy. But if you're making them for a crowd, keep them warm in a low oven (like 200°F) on a wire rack so the bottom doesn't get soggy.

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Chef's Late Night Tips:

  • Grate a little parmesan on the outside of the bread before the final flip
  • Let the pan heat up slowly - patience makes perfect grilled cheese
  • If your cheese isn't melting fast enough, cover the pan with a lid for 30 seconds

This sandwich has saved me from so many sad takeout orders. It's faster than delivery, cheaper than a pizza, and honestly? Way more satisfying. Plus, there's something kind of magical about creating this perfect hybrid of two comfort food classics.

Every time I make these now, I think about all the late-night experiments that led to this recipe. All those 'what if' moments in the kitchen that turned into something that makes people's eyes light up. Because sometimes the best recipes aren't the fancy ones - they're the ones that make you feel like a genius for putting two amazing things together.

Frequently Asked Questions

→ Why pre-cook the pepperoni?
Removes excess grease and makes it crispier.
→ Can I use different cheese?
Yes, any melting cheese works, but mozzarella gives the pizza flavor.
→ What bread is best?
Artesano bread recommended, but any sturdy white bread works.
→ Can I make garlic butter ahead?
Yes, store in fridge and soften before using.
→ Why cook on medium-low heat?
Allows cheese to melt fully without burning the bread.

Pepperoni Pizza Grilled Cheese

A decadent grilled cheese sandwich loaded with mozzarella and pepperoni, enhanced with garlic butter for pizza-like flavor.

Prep Time
5 Minutes
Cook Time
5 Minutes
Total Time
10 Minutes
By: Mena

Category: Main Dishes

Difficulty: Easy

Cuisine: American

Yield: 2 Servings (2 sandwiches)

Dietary: ~

Ingredients

→ Sandwich Base

01 1 tablespoon unsalted butter, for cooking
02 4 slices Sara Lee Artesano Bread
03 4 slices mozzarella cheese, 1/8-inch thick
04 18 slices pepperoni, pre-cooked and dabbed

→ Garlic Butter

05 3 tablespoons unsalted butter
06 1/4 teaspoon fresh or dried parsley
07 1/4 teaspoon Italian seasoning
08 1/4 teaspoon garlic powder
09 1/8 teaspoon salt

→ Optional Toppings

10 Grated parmesan cheese
11 Marinara sauce for dipping

Instructions

Step 01

Microwave pepperoni for 20 seconds and dab off excess grease.

Step 02

Melt butter in skillet over medium-low heat. Place two bread slices in pan.

Step 03

Add one slice mozzarella, 9 pepperoni, and another slice mozzarella to each bread slice. Top with remaining bread.

Step 04

Cook 3 minutes per side until cheese melts.

Step 05

Melt butter and mix with parsley, Italian seasoning, garlic powder, and salt.

Step 06

Brush garlic butter on both sides, cook 30 seconds per side. Optional: sprinkle with parmesan and serve with marinara.

Notes

  1. Pre-cook pepperoni to remove excess grease
  2. Can serve with marinara for dipping

Tools You'll Need

  • Medium skillet
  • Pastry brush
  • Microwave-safe bowl

Allergy Information

Please check ingredients for potential allergens and consult a health professional if in doubt.
  • Dairy (butter, cheese)
  • Gluten (bread)

Nutrition Facts (Per Serving)

It is important to consider this information as approximate and not to use it as definitive health advice.
  • Calories: 625
  • Total Fat: 46 g
  • Total Carbohydrate: 29 g
  • Protein: 22 g